Richard Laurence Millington Synge FRS

FRSE Fellowship of the Royal Society of Edinburgh (FRSE) is an award granted to individuals that the Royal Society of Edinburgh, Scotland's national academy of science and letters, judged to be "eminently distinguished in their subject". This soci ...

FRIC FRSC MRIA (

Liverpool Liverpool is a city and metropolitan borough in Merseyside, England. With a population of in 2019, it is the 10th largest English district by population and its metropolitan area is the fifth largest in the United Kingdom, with a popul ...

, 28 October 1914 –

Norwich Norwich () is a cathedral city and district of Norfolk, England, of which it is the county town. Norwich is by the River Wensum, about north-east of London, north of Ipswich and east of Peterborough. As the seat of the See of Norwich, with ...

, 18 August 1994) was a British

biochemist Biochemists are scientists who are trained in biochemistry. They study chemical processes and chemical transformations in living organisms. Biochemists study DNA, proteins and Cell (biology), cell parts. The word "biochemist" is a portmanteau of ...

, and shared the 1952

Nobel Prize in Chemistry ) , image = Nobel Prize.png , alt = A golden medallion with an embossed image of a bearded man facing left in profile. To the left of the man is the text "ALFR•" then "NOBEL", and on the right, the text (smaller) "NAT•" then "M ...

for the invention of partition

chromatography In chemical analysis, chromatography is a laboratory technique for the separation of a mixture into its components. The mixture is dissolved in a fluid solvent (gas or liquid) called the ''mobile phase'', which carries it through a system (a ...

with

Archer Martin Archer John Porter Martin (1 March 1910 – 28 July 2002) was a British chemist who shared the 1952 Nobel Prize in Chemistry for the invention of partition chromatography with Richard Synge. Early life Martin's father was a GP. Martin was e ...

Life

Richard Laurence Millington Synge was born in

West Kirby West Kirby is a resort town on the north-west corner of the Wirral Peninsula in Merseyside, England, at the mouth of the River Dee, Wales, River Dee. Within the boundaries of the Historic counties of England, historic county of Cheshire, to th ...

on 28 October 1914, the son of Lawrence Millington Synge, a Liverpool stock-broker, and his wife, Katherine C. Swan. Synge was educated at the Old Hall in

Wellington, Shropshire Wellington is a market town in Telford and Wrekin, Shropshire, England. It is situated 4 miles (6 km) northwest of central Telford and 12 miles (19 km) east of Shrewsbury. The summit of The Wrekin lies 3 miles southwest of the town. The ...

and at

Winchester College Winchester College is a public school (fee-charging independent day and boarding school) in Winchester, Hampshire, England. It was founded by William of Wykeham in 1382 and has existed in its present location ever since. It is the oldest of the ...

. He then studied Chemistry at

Trinity College, Cambridge Trinity College is a constituent college of the University of Cambridge. Founded in 1546 by Henry VIII, King Henry VIII, Trinity is one of the largest Cambridge colleges, with the largest financial endowment of any college at either Cambridge ...

. He spent his entire career in research, at the

Wool Industries Research Association The Wool Industries Research Association was an industrial research organization in the United Kingdom. It later became the Wira Technology Group before being merged with the Shirley Institute in the 1989 to form the British Textile Technology Group ...

, Leeds (1941–1943),

Lister Institute for Preventive Medicine The Lister Institute of Preventive Medicine, informally known as the Lister Institute, was established as a research institute (the British Institute of Preventive Medicine) in 1891, with bacteriologist Marc Armand Ruffer as its first director, u ...

, London (1943–1948),

Rowett Research Institute The Rowett Institute is a research centre for studies into Food science, food and nutrition, located in Aberdeen, Scotland. History The institute was founded in 1913 when the University of Aberdeen and the Scottish Agricultural College, Nort ...

, Aberdeen (1948–1967), and

Food Research Institute Food is any substance consumed by an organism for nutritional support. Food is usually of plant, animal, or fungal origin, and contains essential nutrients, such as carbohydrates, fats, proteins, vitamins, or minerals. The substance is inge ...

, Norwich (1967–1976). It was during his time in

Leeds Leeds () is a city and the administrative centre of the City of Leeds district in West Yorkshire, England. It is built around the River Aire and is in the eastern foothills of the Pennines. It is also the third-largest settlement (by populati ...

that he worked with

, developing

partition chromatography Partition chromatography theory and practice was introduced through the work and publications of Archer Martin and Richard Laurence Millington Synge during the 1940s. They would later receive the 1952 Nobel Prize in Chemistry "for their invention ...

, a technique used in the separation mixtures of similar chemicals, that revolutionised analytical chemistry. Between 1942 and 1948 he studied

peptide Peptides (, ) are short chains of amino acids linked by peptide bonds. Long chains of amino acids are called proteins. Chains of fewer than twenty amino acids are called oligopeptides, and include dipeptides, tripeptides, and tetrapeptides. A ...

s of the protein group

gramicidin Gramicidin, also called gramicidin D, is a mix of ionophoric antibiotics, gramicidin A, B and C, which make up about 80%, 5%, and 15% of the mix, respectively. Each has 2 isoforms, so the mix has 6 different types of gramicidin molecules. They c ...

, work later used by

Frederick Sanger Frederick Sanger (; 13 August 1918 – 19 November 2013) was an English biochemist who received the Nobel Prize in Chemistry twice. He won the 1958 Chemistry Prize for determining the amino acid sequence of insulin and numerous other p ...

in determining the structure of

insulin Insulin (, from Latin ''insula'', 'island') is a peptide hormone produced by beta cells of the pancreatic islets encoded in humans by the ''INS'' gene. It is considered to be the main anabolic hormone of the body. It regulates the metabolism o ...

. In March 1950 he was elected a

Fellow of the Royal Society Fellowship of the Royal Society (FRS, ForMemRS and HonFRS) is an award granted by the judges of the Royal Society of London to individuals who have made a "substantial contribution to the improvement of natural science, natural knowledge, incl ...

for which his candidature citation read: In 1963 he was elected a Fellow of the

Royal Society of Edinburgh The Royal Society of Edinburgh is Scotland's national academy of science and letters. It is a registered charity that operates on a wholly independent and non-partisan basis and provides public benefit throughout Scotland. It was established i ...

. His proposers were

Magnus Pyke Magnus Alfred Pyke (29 December 1908 – 19 October 1992) was an English nutritional scientist, governmental scientific adviser, writer and presenter. He worked for the UK Ministry of Food, the post-war Allied Commission for Austria, and diff ...

, Andrew Phillipson, Sir

David Cuthbertson Sir David Paton Cuthbertson, CBE, FRSE (9 May 1900 – 15 April 1989) was a Scottish physician, biochemist, medical researcher and nutritionist who was a leading authority on metabolism. The Rowett Research Institute became one of the world ...

and John Andrew Crichton. He was for several years the treasurer of the Chemical Information Group of the

Royal Society of Chemistry The Royal Society of Chemistry (RSC) is a learned society (professional association) in the United Kingdom with the goal of "advancing the chemistry, chemical sciences". It was formed in 1980 from the amalgamation of the Chemical Society, the Ro ...

, and was an honorary Professor in Biological Sciences at the

University of East Anglia The University of East Anglia (UEA) is a public research university in Norwich, England. Established in 1963 on a campus west of the city centre, the university has four faculties and 26 schools of study. The annual income of the institution f ...

from 1968 to 1984. He was awarded an honorary Doctor of Science (ScD) from the

in 1977, and an honorary doctorate from the Faculty of Mathematics and Science at

Uppsala University Uppsala University ( sv, Uppsala universitet) is a public university, public research university in Uppsala, Sweden. Founded in 1477, it is the List of universities in Sweden, oldest university in Sweden and the Nordic countries still in opera ...

, Sweden in 1980.

Personal life

In 1943 Synge married Ann Davies Stephen (1916–1997). Ann Stephen was the daughter of psychologist Karin Stephen and psychoanalyst

Adrian Stephen Adrian Leslie Stephen (27 October 1883 – 3 May 1948) was a member of the Bloomsbury Group, an author and psychoanalyst, and the younger brother of Thoby Stephen, Virginia Woolf and Vanessa Bell. He and his wife Karin Stephen became interest ...

. Ann's sister Judith (1918-1972) was married to documentary artist and photographer

Nigel Henderson Admiral Sir Nigel Stuart Henderson, (1 August 1909 – 2 August 1993) was a Royal Navy officer who served as Chairman of the NATO Military Committee from 1968 to 1971. Naval career Henderson joined the Royal Navy in 1927.

References

External links

* * Synge's Nobel Lectur
Applications of Partition Chromatography
* {{DEFAULTSORT:Synge, Richard 1914 births 1994 deaths People educated at Winchester College Alumni of Trinity College, Cambridge British biochemists Nobel laureates in Chemistry British Nobel laureates Scientists from Liverpool Academics of the University of East Anglia Fellows of the Royal Society English Nobel laureates